nirmatrelvir will raise the degree or result of triazolam by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Contraindicated.Stiripentol is usually a CYP3A4 inhibitor and inducer. Monitor CYP3A4 substrates coadministered with stiripentol for amplified or diminished results. CYP3A4 substrates may possibly call for dosage adjustment.telotrista